Reactome

Integrates with Reactome's curated biological pathway database to search pathways by keywords, genes, or diseases, retrieve detailed pathway information and biochemical reactions, explore pathway hierarchies, and analyze protein interactions for systems biology research and drug discovery workflows.

This production-ready MCP server provides access to Reactome's curated biological pathway database through eight specialized tools for systems biology analysis. Developed by Augmented Nature, it enables searching for pathways by keywords, genes, or diseases, retrieving detailed pathway information including participants and biochemical reactions, exploring pathway hierarchies, and analyzing protein interactions within biological networks. The implementation uses Reactome's Content Service API with robust error handling, pathway ID resolution, and structured data formatting, making it valuable for bioinformatics research, drug discovery workflows, and AI systems performing molecular pathway analysis.